Fioricet Breastfeeding Warnings

Acetaminophen, butalbital, and caffeine are excreted into human milk in small concentrations. The significance of the effects on nursing infants has not been reported, but due to the potential for serious adverse reactions in nursing infants, other agents may be preferred.

A decision should be made to discontinue breastfeeding or discontinue the drug, taking into account the importance of the drug to the mother.

Excreted into human milk: Yes (acetaminophen); Yes (barbiturates); Yes (caffeine)

Effects in Breastfed Infants
The mother of a newborn took a product containing acetaminophen 325 mg, butalbital 50 mg, and caffeine 40 mg every 6 hours for 24 hours for a spinal headache, with the last dose a day prior to presentation at the emergency department. Her 7-day-old infant had a history of 1 to 2 days of poor feeding, lethargy and vomiting. The infant was somnolent, lethargic, and demonstrating diminished reflexes. The urine was qualitatively positive for barbiturate and had also had 1 mg/L of caffeine 15 hours after hospital admission. The infant’s symptoms resolved within 24 hours. The symptoms were probably caused by butalbital.

If you are PREGNANT

  • No Known Fetal/Neonatal Risk:
  • FDA C (unknown human fetal risk; assess risk/benefit):
  • FDA C (unknown human fetal risk; assess risk/benefit):

If you are NURSING

  • Precaution: HIGH DOSES MAY CAUSE HYPERACTIVITY AND WAKEFULNESS IN INFANT.
  • Precaution: POSSIBILITY OF CENTRAL NERVOUS SYSTEM DEPRESSION IN NURSING INFANT.
  • No Known Risk: LOW LEVELS EXCRETED WITH LOW RISK FOR ADVERSE EFFECTS IN INFANT

If you are an adult over 60

  • management or monitoring precaution: General-Not recommended in the elderly due to sedation which may predispose to falls. May exacerbate depression. Renal-Renal excretion may increase adverse events with renal impairment. Monitor renal function.
  • management or monitoring precaution: Hepatic-Elderly may be more susceptible to hepatotoxicity. Strict adherence to a maximum daily dose is recommended, and the maximum dose recommendation varies between 3000-3800 mg depending on strength used and source of the recommendation.
Fioricet
Fioricet

Giving Fioricet to a child under 12

  • management or monitoring precaution: Use weight based dosing in children less than 12 years.
  • management or monitoring precaution: Adverse CNS effects (e.g. insomnia, restlessness, nervousness, and mild delirium) may be more severe in children.
  • Severe Precaution: Safety and effectiveness not established age < 12 years.
  • management or monitoring precaution: Caution in infants with seizure disorder, cardiovascular disease, renal impairment, or hepatic impairment.

Buspirone side effects

In Summary

Commonly reported side effects of buspirone include: dizziness. Other side effects include: headache and nervousness. See below for a comprehensive list of adverse effects.

Applies to buspirone: oral tablet

Along with its needed effects, buspirone may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking buspirone:

Rare

  • Chest pain
  • confusion
  • fast or pounding heartbeat
  • fever
  • incoordination
  • mental depression
  • muscle weakness
  • numbness, tingling, pain, or weakness in the hands or feet
  • skin rash or hives
  • sore throat
  • stiffness of the arms or legs
  • uncontrolled movements of the body

Get emergency help immediately if any of the following symptoms of overdose occur while taking buspirone:

Symptoms of overdose

  • Dizziness or lightheadedness especially when getting up from a sitting or lying position suddenly
  • drowsiness (severe)
  • loss of consciousness
  • nausea or vomiting
  • stomach upset
  • very small pupils of the eyes

Some side effects of buspirone may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Restlessness, nervousness, or unusual excitement

Less common or rare

  • Blurred vision
  • clamminess or sweating
  • decreased concentration
  • diarrhea
  • drowsiness
  • dryness of the mouth
  • muscle pain, spasms, cramps, or stiffness
  • ringing in the ears
  • trouble with sleeping, nightmares, or vivid dreams
  • unusual tiredness or weakness

For Healthcare Professionals

Applies to buspirone: compounding powder, oral tablet

Nervous system

Very common (10% or more): Dizziness (12%), drowsiness (10%)

Common (1% to 10%): Lightheadedness, decreased concentration, numbness, paresthesia, incoordination, headache, tremor, syncope, seizures

Rare (less than 0.1%): Cerebrovascular accident

Very rare (less than 0.01%): Serotonin syndrome, amnesia, cogwheel rigidity, dystonia/dystonic reactions, dyskinesias (acute and tardive), ataxias, parkinsonism, akathisia, restless leg syndrome

Postmarketing reports: Vertigo, extrapyramidal symptoms, transient difficulty with recall[Ref]

Cardiovascular

Common (1% to 10%): Tachycardia/palpitations, chest pain

Uncommon (0.1% to 1%): Hypotension, hypertension

Rare (less than 0.1%): Congestive heart failure, myocardial infarction, cardiomyopathy, bradycardia[Ref]

Dermatologic

Common (1% to 10%): Rash, sweating/clamminess

Uncommon (0.1% to 1%): Pruritus, flushing, easy bruising, hair loss, dry skin, facial edema, blisters

Rare (less than 0.1%): Acne, thinning of nails, ecchymosis, urticaria[Ref]

Gastrointestinal

Common (1% to 10%): Nausea, dry mouth, abdominal/gastric distress, diarrhea, constipation, vomiting

Uncommon (0.1% to 1%): Flatulence, anorexia, increased appetite, salivation, irritable colon, rectal bleeding

Rare (less than 0.1%): Burning of the tongue[Ref]

Musculoskeletal

Common (1% to 10%): Musculoskeletal aches/pains

Uncommon (0.1% to 1%): Muscle cramps, muscle spasms, rigid/stiff muscles, arthralgias

Rare (less than 0.1%): Muscle weakness[Ref]

Ocular

Common (1% to 10%): Blurred vision

Uncommon (0.1% to 1%): Eye redness and itching, conjunctivitis, eye pain, eye pressure, photophobia

Very rare (less than 0.01%): Visual changes (including tunnel vision)[Ref]

Other

Common (1% to 10%): Fatigue, weakness, tinnitus, sore throat

Uncommon (0.1% to 1%): Altered taste, altered smell, inner ear abnormality, edema, fever, roaring sensation in the head, malaise

Rare (less than 0.1%): Alcohol abuse, loss of voice, hiccoughs[Ref]

Psychiatric

Common (1% to 10%): Insomnia, nervousness, excitement, anger/hostility, confusion, depression, dream disturbances, attention disturbance, sleep disorder

Uncommon (0.1% to 1%): Depersonalization, dysphoria, noise intolerance, euphoria, akathisia, fearfulness, loss of interest, dissociative reaction, hallucinations, involuntary movements, slowed reaction time, suicidal ideation, decreased or increased libido

Rare (less than 0.1%): Claustrophobia, cold intolerance, stupor, slurred speech, psychosis, delayed ejaculation, impotence

Very rare (less than 0.01%): Depersonalization

Postmarketing reports: Emotional lability, restlessness[Ref]

Respiratory

Common (1% to 10%): Nasal congestion, pharyngolaryngeal pain

Uncommon (0.1% to 1%): Hyperventilation, shortness of breath, chest congestion

Rare (less than 0.1%): Epistaxis[Ref]

Genitourinary

Uncommon (0.1% to 1%): Urinary frequency, urinary hesitancy, menstrual irregularity and spotting, dysuria

Rare (less than 0.1%): Amenorrhea, pelvic inflammatory disease, enuresis, nocturia

Very rare (less than 0.01%): Urinary retention[Ref]

Hepatic

Uncommon (0.1% to 1%): Increases in hepatic aminotransferases (SGOT, SGPT)[Ref]

Metabolic

Uncommon (0.1% to 1%): Weight gain, weight loss[Ref]

Endocrine

Rare (less than 0.1%): Galactorrhea, thyroid abnormality[Ref]

Hematologic

Rare (less than 0.1%): Eisonophilia, leukopenia, thrombocytopenia, bleeding disturbance[Ref]

Hypersensitivity

Postmarketing reports: Allergic reactions, angioedema[Ref]

References

1. “Product Information. Buspar (buspirone).” Bristol-Myers Squibb, Princeton, NJ.

2. Cerner Multum, Inc. “UK Summary of Product Characteristics.” O 0

3. Cerner Multum, Inc. “Australian Product Information.” O 0

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Barbiturate Withdrawal Following Internet Purchase of Fioricet

Who can not buy fioricet in our website online ?

All the pharmacies in our warehouses are US licensed pharmacies and you can get the pharmacy name, the pharmacists name and the doctor name in the bottle we sent you.

You can also get the full prescription profile when you buy the prescription in our online pharmacies. But we do not ship to all patients:

    • The first time buyer. We do not sell to patient who has not seen a local doctors that prescribed him a Fioricet prescription;
    • The patient has a history of mental illness or suicidal thoughts;
    • The patient has liver disease;
    • The patient has heart disease;
    • The patient has kidney disease;
    • The patient has drug or alcohol addiction history;
    • The patient has taken a MAO inhibitor in the past 14 days;
    • The patient is allergic to acetaminophen, butalbital, or caffeine;
    • The patient has cirrhosis disease;
    • The patient has asthma, sleep apnea, or other breathing disorder;
    • The patient has stomach ulcer or bleeding;
    • The patient has a history of skin rash caused by any medication;
    • The patient uses medicine to prevent blood clots
    • The patient is pregnant; life-threatening withdrawal symptoms in the baby after it is born
    • The patient is breastfeeding because this medicine can pass into breast milk and may harm a nursing baby.

You  cannot order in our website if you

    • have not picked up after clicking placing order button;
    • send us a bounced check;
    • send us a check not money order;
    • keep emailing us for a single order ID
    • asked a charge back before

Background  The Internet enables businesses to advertise their pharmaceutical products and services without medical supervision. The Internet also allows for the unsupervised purchase of medications that may have neurologic consequences.

Objective  To describe acute withdrawal delirium following the abrupt discontinuation of Fioricet.

Patient  The patient was a 37-year-old woman with a history of depression and migraine headaches but not drug abuse. She developed a florid withdrawal delirium following the discontinuation of a drug she purchased online. The medication, which contained butalbital, was self-administered in escalating doses for the treatment of chronic headaches. Daily doses of up to 750 mg to 1000 mg were reported.

Results  The patient was admitted to the hospital for the treatment of unexplained seizures that were followed by several days of an intense withdrawal syndrome. Little improvement was noted after the administration of benzodiazepines and phenothiazine. After parenteral phenobarbital administration, her symptoms resolved.

Conclusions  The withdrawal state from barbiturates is similar to that from ethanol. Tolerance can develop with prolonged abuse, leading to escalating drug doses to achieve the desired effect.

The suggested management of both types of withdrawal syndromes is similar, but the relative resistance of the behavioral and autonomic features in patients was remarkable.

Physicians should be aware of the ease with which medications can be purchased without supervision from Internet pharmacies. The magnitude of the number of drugs that are made available through this means creates a proclivity to withdrawal states.